Can humans live to 175 years old with technologies and treatments that have become available in the last 3 years?
If you were a healthy human that would have lived 90 years without implementing these 3 discoveries, implementing all of them at birth would give you a 175 year lifespan.
The following studies were published in major peer-reviewed journals and demonstrated ability to affect dramatic improvements in the health,strength, and lifespans of mice. All three of these findings were reported far and wide across scientific and medical journals (links below).
1) Scientists find that administering the new form of Vitamin B3 called Nicotinamide Riboside significantly improved levels of "NAD+" [and improved lifespan and health in animals]
The oxidized form of cellular nicotinamide adenine dinucleotide (NAD+) is critical for mitochondrial function, and its supplementation can lead to increased longevity. Zhang et al. found that feeding the NAD+ precursor nicotinamide riboside (NR) to aging mice protected them from muscle degeneration (see the Perspective by Guarente). NR treatment enhanced muscle function and also protected mice from the loss of muscle stem cells. The treatment was similarly protective of neural and melanocyte stem cells, which may have contributed to the extended life span of the NR-treated animals.
Link 2: https://www.nature.com/articles/ncomms12948
Link 3: http://observer.com/2017/07/elysium-health-basis-nad-supplement/ This Bio-Hacking Anti-Aging Product Has a Unique Cult Following: Doctors
Link 4: https://www.nature.com/articles/ncomms12948 Nicotinamide riboside is uniquely and orally bioavailable in mice and humans
Link 5: https://www.sciencedaily.com/releases/2016/04/160428152124.htm Vitamin stops the aging process of organs -- Nicotinamide riboside rejuvenates stem cells, allowing better regeneration processes in aged mice
2) Hypothalamic Stem Cells Control Aging in Mice link
In a study in mice, a research team at Albert Einstein College of Medicine has found that stem cells in the hypothalamus, a region of the brain that controls an immense number of bodily functions, govern how fast aging occurs in the body.
This treatment significantly slowed aging in both groups of animals as measured by tissue analysis and behavioral testing that involved assessing changes in the animals’ muscle endurance, coordination, social behavior and cognitive ability.
Link 2: http://www.nature.com/nature/journal/v548/n7665/full/nature23282.html Hypothalamic stem cells control ageing speed partly through exosomal miRNAs
Link 3: https://singularityhub.com/2017/08/06/these-stem-cells-are-key-to-controlling-aging/ Breakthrough Stem Cell Study Offers New Clues to Reversing Aging
Link 4: http://www.independent.co.uk/news/science/reverse-ageing-stem-cells-brain-hypothalamus-slow-extend-human-lifespan-dongsheng-cai-albert-a7861746.html Stem cells in brain located by scientists could help reverse ageing process
Link 5: https://arstechnica.com/science/2017/07/neural-stem-cells-linked-to-maintenance-of-youth/ Specific area of the brain helps keep the body young -- Your hypothalamus might be the actual fountain of youth.
3) Promising New Therapy Extends Lifespans of Mice by 35 Percent
With this in mind, researchers at the Mayo Clinic found a way to destroy these worn-out cells in normal mice, extending their lifespan by as much as 25 to 35 percent. Excitingly, this aging process applies to humans as well, giving hope to potential life-extending therapies. The details of this work can now be found in the latest edition of Nature.
The problem with senescent cells is at least twofold. First, their inability to divide properly means they’re no longer contributing to the growth of healthy tissue. Second, these stressed-out cells pollute the body, damaging healthy cells nearby. The result is chronic inflammation, which is closely linked to frailty and other age-related diseases. Tellingly, the accumulation of abnormal amounts of senescent cells tends to happen where disease occurs, including in our lungs, joints, and arteries.
Link 2: https://www.theatlantic.com/science/archive/2016/02/clearing-retired-cells-extends-life/459723/ Clearing the Body's Retired Cells Slows Aging and Extends Life -- A series of experiments in mice has led to what some are calling “one of the more important aging discoveries ever."
Link 3: https://www.technologyreview.com/s/600705/in-new-anti-aging-strategy-clearing-out-old-cells-increases-life-span-of-mice-by-25-percent/ In New Anti-Aging Strategy, Clearing Out Old Cells Increases Life Span of Mice by 25 Percent -- As we get older, some of our cells stop dividing. Are these derelicts a reason we age?
Link 4: http://www.popularmechanics.com/science/health/a19277/scientists-can-now-radically-expand-the-lifespan-of-mice-are-humans-next/ Scientists Can Now Radically Expand the Lifespan of Mice—and Humans May Be Next | Medical researchers at Mayo Clinic have made this decade's biggest breakthrough in understanding the complex world of physical aging.
Link 5: http://www.newsweek.com/scientists-extend-life-35-percent-mice-clearing-cellular-litter-422703 SCIENTISTS EXTEND LIFE BY 35 PERCENT IN MICE BY CLEARING CELLULAR ‘LITTER’